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A pea-sized endocrine gland at the base of the brain that produces growth hormone, ACTH, TSH, and other hormones regulating crucial body functions.
The pituitary gland is a small endocrine organ at the base of the brain, connected to the hypothalamus by the pituitary stalk. Often called the 'master gland', it is divided into the anterior pituitary (producing GH, ACTH, TSH, FSH, LH, and prolactin) and posterior pituitary. The pituitary is the primary target of growth hormone secretagogue peptides: CJC-1295 stimulates GH release by activating GHRH receptors on pituitary somatotroph cells, while Ipamorelin activates GHS-R1a receptors on the same cells. These provide complementary stimulation through distinct intracellular signalling pathways.
BIOLOGY
General research term
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A 191-amino acid peptide hormone secreted by the anterior pituitary gland that regulates growth, body composition, metabolism, and tissue repair.
Growth Hormone-Releasing Hormone, a 44-amino acid peptide produced in the hypothalamus that stimulates growth hormone synthesis and secretion from the pituitary.
A synthetic 29-amino acid analogue of growth hormone-releasing hormone (GHRH) that stimulates sustained growth hormone elevation from the pituitary gland.
A selective pentapeptide growth hormone secretagogue that stimulates GH release via the ghrelin receptor with minimal effects on cortisol and prolactin.
The branch of medicine and biology concerned with the endocrine system, hormones, and their roles in regulating metabolism, growth, and reproduction.
The active growth phase of the hair follicle cycle, lasting 2-7 years, during which the hair shaft elongates from a fully formed hair bulb.
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