A 28-amino acid peptide hormone primarily produced in the stomach that stimulates appetite and growth hormone release via the GHS-R1a receptor.
Ghrelin is a 28-amino acid peptide hormone predominantly synthesised by enteroendocrine cells of the gastric fundus, earning it the designation as the 'hunger hormone'. It acts as the endogenous ligand for the growth hormone secretagogue receptor type 1a (GHS-R1a), stimulating both appetite and growth hormone (GH) release from the anterior pituitary gland. Ghrelin undergoes a unique post-translational modification called octanoylation at its third serine residue, which is essential for its ability to bind GHS-R1a and cross the blood-brain barrier. Beyond appetite regulation and GH secretion, ghrelin plays roles in glucose metabolism, gastrointestinal motility, cardiovascular protection, and immune modulation. Synthetic peptides like Ipamorelin mimic ghrelin's GH-releasing action while being more selective for the GHS receptor, avoiding ghrelin's broader appetite-stimulating and cortisol-elevating effects.
A selective pentapeptide growth hormone secretagogue that stimulates GH release via the ghrelin receptor with minimal effects on cortisol and prolactin.
A 191-amino acid peptide hormone secreted by the anterior pituitary gland that regulates growth, body composition, metabolism, and tissue repair.
Growth Hormone-Releasing Hormone, a 44-amino acid peptide produced in the hypothalamus that stimulates growth hormone synthesis and secretion from the pituitary.
A molecule that binds to and activates a cellular receptor, mimicking or enhancing the effect of the natural signalling molecule (ligand).
The fundamental building blocks of peptides and proteins, with 20 standard types that combine in unique sequences to create biologically active molecules.
Body Protection Compound-157, a synthetic 15-amino acid peptide derived from human gastric juice with potent tissue-healing and neuroprotective properties.
Legal under MHRA rules. BPC-157, tirzepatide & NAD+ pens with next-day UK delivery from £99. >99% purity, GMP certified. Shop now.
ARTICLEPens cut dosing error from 15% to under 2%. We compare accuracy, contamination risk, cost, and convenience. See why researchers are switching in 2026.
ARTICLEOver 100 published studies back BPC-157 for tissue repair, gut healing, and neuroprotection. Mechanisms, dosing protocols, and where to buy in the UK.
COMPARISONCompare BPC-157 and TB-500 for recovery research. Mechanisms, benefits, dosing, and when to use each peptide. Buy both as pre-mixed pens UK.
COMPARISONCompare tirzepatide and semaglutide for metabolic research. Dual vs single receptor, efficacy data, side effects, and pricing. Buy tirzepatide pens UK.
ENCYCLOPEDIAGastric Pentadecapeptide. Molecular weight: 1419.53 Da. Explore mechanism of action, key studies, and research applications.
BUNDLEThe most studied peptide duo in tissue regeneration research
PROTOCOLResearch protocol combining BPC-157 and TB-500 peptide pens for accelerated tissue recovery. Explore synergistic healing mechanisms, dosing schedules, and published study findings.
FAQEverything you need to know about peptide pen systems. Learn how pre-mixed peptide pens work, their advantages over vials, dosing mechanisms, and more.
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